Tuesday, May 02, 2006 |
A CENTURY OF ALZHEIMER'S |
** 1901 Dr. Alois Alzheimer examines 51 year old Aguste D. and diagnoses what he coins "presenile dementia".
** 1906 Dr. Emil Kraepelin rewards protege by naming "Alzheimer's disease" for him.
** 1936 Scientist's find same plaques and tangles in middle-aged and elderly brains.
** 1963 Researchers link cognitive decline to plaques and tangles.
** 1974 Old term "senile dementia" replaced by diagnosis of "Alzheimer's disease".
** 1975 Verbal cognitive test introduced as standard diagnostic tool.
** 1979 Alzheimer's Association formed to help patients and caregivers.
** 1980 Rita Hayworth's diagnosis makes Alzheimer's widely known worldwide.
** 1983 President Reagan approves task force for Alzheimer's research.
** 1984 Beta-amyloid identified as component of plaques between neurons.
** 1990 Tau protein identified as component tangles within neurons.
** 1991 First gene implicated in early-onset Alzheimer's.
** 1992 First gene implication as risk factor in late-onset Alzheimer's.
** 1993 FDA approves first Alzheirmers' drug, tacrine (Cognex), for mild to moderate symptoms.
** 1994 Former President Reagan announces diagnosis of Alzheimer's.
** 1996 Donepezil (Aricept) approved by FDA as safer treatment for mild to moderate symptoms and becomes most popular Alzheimer's drug.
** 1999 First Alzheimer's vaccine tested in mice but side effects halt human trials.
** 2003 Memantine (Nemenda) approved by FDA as first drug to treat moderate to severe Alzheimer's symptoms.
** 2004 U.S. government approves PET brain scans to diagnose Alzheimer's.
(Source: NEUROLOGY NOW MAG) |
posted by infraternam meam @ 2:37 PM |
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