| Tuesday, May 02, 2006
| A CENTURY OF ALZHEIMER'S
Dr. Alois Alzheimer examines 51 year old Aguste D. and diagnoses what he coins "presenile dementia".
Dr. Emil Kraepelin rewards protege by naming "Alzheimer's disease" for him.
Scientist's find same plaques and tangles in middle-aged and elderly brains.
Researchers link cognitive decline to plaques and tangles.
Old term "senile dementia" replaced by diagnosis of "Alzheimer's disease".
Verbal cognitive test introduced as standard diagnostic tool.
Alzheimer's Association formed to help patients and caregivers.
Rita Hayworth's diagnosis makes Alzheimer's widely known worldwide.
President Reagan approves task force for Alzheimer's research.
Beta-amyloid identified as component of plaques between neurons.
Tau protein identified as component tangles within neurons.
First gene implicated in early-onset Alzheimer's.
First gene implication as risk factor in late-onset Alzheimer's.
FDA approves first Alzheirmers' drug, tacrine (Cognex), for mild to moderate symptoms.
Former President Reagan announces diagnosis of Alzheimer's.
Donepezil (Aricept) approved by FDA as safer treatment for mild to moderate symptoms and becomes most popular Alzheimer's drug.
First Alzheimer's vaccine tested in mice but side effects halt human trials.
Memantine (Nemenda) approved by FDA as first drug to treat moderate to severe Alzheimer's symptoms.
U.S. government approves PET brain scans to diagnose Alzheimer's.
(Source: NEUROLOGY NOW MAG)
|posted by infraternam meam @ 2:37 PM